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Supplements for Rumination and Intrusive Thoughts: What Reddit Users Report

This ranking reflects what people who mention rumination, intrusive thoughts or OCD report in Reddit comments: 79 owner comments, ranked by a context rating that shrinks small samples toward the average. It is not a recommendation to try any of them. Persistent or severe symptoms need a doctor's assessment. Vitamin D and B vitamins are left out as background pages.

#SupplementContext ratingRated comments herePositiveNegativeOverall score
1Saffron extract (incl. Affron)3.85504.0
2NAC (N-acetylcysteine)3.5251533.2
3Magnesium (form not stated)3.43214.1
4Inositol3.35323.5
5Magnesium glycinate3.33214.0
6L-theanine3.33214.0
7Glycine3.03123.0

In their words

4/5 Calming effect

“So sorry you're experiencing this...I was dealing with the exact same a few days ago...I will tell you Saffron majorly helps ease anxiety & Id be a wreck without it...might be worth looking into...I only take a few threads with warm water…”

owner comment via r/Anxiety · 2026-09-10 · 1 upvotes
4/5

“I take NAC mostly for glutathione production, but I also have extreme OCD.”

owner comment via r/Supplements · 2026-05-12 · 6 upvotes
4/5

“If you have OCD, myo-inositol might help a lot too.”

owner comment via r/Supplements · 2026-09-09 · 2 upvotes
4/5

“As a person with OCD, Taurine and NAC, and maybe Theanine, helped me feel the best.”

owner comment via r/Supplements · 2026-06-08 · 1 upvotes

Mixed and negative reports

2/5 Fast-actingStomach upset

“It really depends on what you're taking NAC for.”

owner comment via r/Supplements · 2026-10-12 · 1 upvotes
2/5

“You could be having an adverse reaction to the magnesium OR the glycine.”

owner comment via r/Supplements · 2026-06-01 · 2 upvotes

Before you try anything