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Question · Everyday stress

Does magnesium glycinate help with stress?

Many say yes, going by Reddit owner reports: 33 of 39 rated comments from people who describe everyday stress or feeling overwhelmed describe a good experience with Magnesium glycinate, and 4 describe a poor one. That is self-reported experience, not proof that it works, and results vary from person to person.

Magnesium glycinate, Everyday stress	Owner comments
Rated comments in this context	39
Positive	33 (85%)
Negative	4 (10%)
Describe an unwanted effect	5
Context rating (small samples pulled to the average)	3.7

Magnesium glycinate overall: 4.0 from 370 owner comments in Reddit anxiety, stress and supplement communities, May 2026 to October 2026.

What the research says

Magnesium glycinate (bisglycinate) is magnesium bound to the amino acid glycine.^{[NIH Office of Dietary Supplements]}
Absorption studies have compared organic forms such as diglycinate with magnesium oxide.^[PubMed]^[PubMed]

Safety

The NIH upper limit for magnesium from supplements is 350 mg a day for adults; higher doses commonly cause diarrhea, nausea and abdominal cramping.^{[NIH Office of Dietary Supplements]}
Magnesium can reduce the absorption of some antibiotics (tetracyclines, quinolones) and bisphosphonates, so the NIH advises spacing the doses apart.^{[NIH Office of Dietary Supplements]}

Good experiences

4/5
“Magnesium glycinate, improved my sleep, fewer muscle twitches, and helped me feel less tension etc.”

owner comment via r/Supplements · 2026-05-11 · 28 upvotes

4/5 Stomach upsetTaste & form
“i switched from citrate to glycinate about 6 months ago and for me the difference was noticeable.”

owner comment via r/Supplements · 2026-07-09 · 3 upvotes

5/5 Mood
“I'm not a woman but I had similar energy crash and mood swing from work stress, magnesium glycinate before sleep made huge difference for me”

owner comment via r/Supplements · 2026-07-05 · 8 upvotes

Poor experiences

2/5 Falling asleepTakes time
“Started magnesium glycinate for sleep, didn't really knock me out but after two weeks I noticed my jaw wasn't clenched into a fist all day.”

owner comment via r/Supplements · 2026-08-13 · 35 upvotes

2/5 Stopped working
“At the time though I a) got really ill and stopped working there b) started iron and magnesium glycinate and c) now know I'm audhd so know a lot more about my burn out levels.”

owner comment via r/sleep · 2026-10-13 · 2 upvotes

How reports compare in other contexts

Context	Rated comments	Positive	Negative
Anxiety & worry	75	43	23
Low mood	24	13	10
Panic attacks	12	8	2
Physical tension	8	6	2

More on Magnesium glycinate

Talk to a doctor about new, severe or lasting symptoms, and to a pharmacist before combining supplements with medicines.